SOVEREIGN PROOF ENGINE

Total Predictions
29,627,537
Unique Scaffolds
5,730,087
Blockchain Batches
2,158
Enriched Molecules
16,387,882
VAULT-Tier Compounds
232,978
Top 0.5% — sovereign-grade binding affinity
Prediction Velocity
163,920
New predictions in last 24 hours

KNOWN DRUGS DISCOVERED

Axiom independently identified these pharmaceutical compounds — validating model accuracy

NSAID

Aspirin

1.0000
Binding Score
NSAID

Ibuprofen

1.0000
Binding Score
Polyphenol

Caffeic Acid

1.0000
Binding Score
Purine

Uric Acid

0.4533
Binding Score

MOLECULAR ANALYTICS

Binding Score Distribution
LogP Distribution
SCINS Traffic Light
Lipinski Violations

COMPOUND QUALITY FUNNEL

ENRICHMENT PASS RATES

Lipinski Pass
33.2%
Veber Pass
3.5%
PAINS Clean
36.6%
Lead-like
0.3%

QUALITY PIPELINE

DRUG-LIKENESS PROFILE

Drug-likeness Radar
ADMET Traffic Light
Pharmacokinetic assessment (distinct from SCINS structural classification)

DATA TIER BREAKDOWN

DISCOVERY 11,298,157
ENTERPRISE 10,181,973
PROFESSIONAL 7,914,429

CATEGORY BREAKDOWN

Category Counts
peptide-like 18,359,536
drug-like 11,244,715
fragment 23,286

TOP MURCKO SCAFFOLDS

Scaffold structures are available through partnership engagements — labs@smartledger.solutions

# Scaffold Count Avg Binding
1 🔒 partnership-gated 34,331 0.5623
2 🔒 partnership-gated 30,290 0.3794
3 🔒 partnership-gated 30,192 0.4554
4 🔒 partnership-gated 25,338 0.4974
5 🔒 partnership-gated 23,121 0.4521
6 🔒 partnership-gated 13,531 0.4477
7 🔒 partnership-gated 11,119 0.2751
8 🔒 partnership-gated 10,990 0.5912
9 🔒 partnership-gated 9,760 0.2875
10 🔒 partnership-gated 9,550 0.4244
Partnership Access
Compound dossiers, ADMet profiles, scaffold data, and bulk exports are available through partnership engagements with our research team.