SOVEREIGN PROOF ENGINE
Total Predictions
28,986,812
Unique Scaffolds
5,593,540
Blockchain Batches
2,158
Enriched Molecules
15,889,040
VAULT-Tier Compounds
221,865
Top 0.5% — sovereign-grade binding affinity
Prediction Velocity
163,920
New predictions in last 24 hours
KNOWN DRUGS DISCOVERED
Axiom independently identified these pharmaceutical compounds — validating model accuracy
NSAID
Aspirin
1.0000
Binding Score
NSAID
Ibuprofen
1.0000
Binding Score
Polyphenol
Purine
Caffeic Acid
1.0000
Binding Score
Uric Acid
0.4533
Binding Score
MOLECULAR ANALYTICS
Binding Score Distribution
LogP Distribution
SCINS Traffic Light
Lipinski Violations
COMPOUND QUALITY FUNNEL
ENRICHMENT PASS RATES
Lipinski Pass
34.2%
Veber Pass
3.5%
PAINS Clean
34.6%
Lead-like
0.3%
QUALITY PIPELINE
DRUG-LIKENESS PROFILE
Drug-likeness Radar
ADMET Traffic Light
Pharmacokinetic assessment (distinct from SCINS structural classification)
DATA TIER BREAKDOWN
DISCOVERY 11,123,807
ENTERPRISE 9,879,477
PROFESSIONAL 7,761,621
CATEGORY BREAKDOWN
Category Counts
peptide-like
17,869,336
drug-like
11,094,325
fragment
23,151
TOP MURCKO SCAFFOLDS
Scaffold structures are available through partnership engagements — labs@smartledger.solutions
| # | Scaffold | Count | Avg Binding |
|---|---|---|---|
| 1 | 🔒 partnership-gated | 33,817 | 0.5591 |
| 2 | 🔒 partnership-gated | 30,139 | 0.3775 |
| 3 | 🔒 partnership-gated | 29,966 | 0.4531 |
| 4 | 🔒 partnership-gated | 25,196 | 0.4959 |
| 5 | 🔒 partnership-gated | 22,891 | 0.4489 |
| 6 | 🔒 partnership-gated | 13,411 | 0.4449 |
| 7 | 🔒 partnership-gated | 11,112 | 0.2748 |
| 8 | 🔒 partnership-gated | 10,840 | 0.5887 |
| 9 | 🔒 partnership-gated | 9,754 | 0.2872 |
| 10 | 🔒 partnership-gated | 9,382 | 0.4183 |
Partnership Access
Compound dossiers, ADMet profiles, scaffold data, and bulk exports are available through partnership engagements with our research team.