SOVEREIGN PROOF ENGINE

Total Predictions
34,002,677
Unique Scaffolds
6,218,972
Blockchain Batches
2,158
Enriched Molecules
18,495,293
VAULT-Tier Compounds
306,660
Top 0.5% — sovereign-grade binding affinity
Prediction Velocity
163,920
New predictions in last 24 hours

KNOWN DRUGS DISCOVERED

Axiom independently identified these pharmaceutical compounds — validating model accuracy

NSAID

Aspirin

1.0000
Binding Score
NSAID

Ibuprofen

1.0000
Binding Score
Polyphenol

Caffeic Acid

1.0000
Binding Score
Purine

Uric Acid

0.4533
Binding Score

MOLECULAR ANALYTICS

Binding Score Distribution
LogP Distribution
SCINS Traffic Light
Lipinski Violations

COMPOUND QUALITY FUNNEL

ENRICHMENT PASS RATES

Lipinski Pass
29.8%
Veber Pass
3.8%
PAINS Clean
43.7%
Lead-like
0.4%

QUALITY PIPELINE

DRUG-LIKENESS PROFILE

Drug-likeness Radar
ADMET Traffic Light
Pharmacokinetic assessment (distinct from SCINS structural classification)

DATA TIER BREAKDOWN

DISCOVERY 12,513,515
ENTERPRISE 12,216,749
PROFESSIONAL 8,965,753

CATEGORY BREAKDOWN

Category Counts
peptide-like 21,658,972
drug-like 12,319,562
fragment 24,143

TOP MURCKO SCAFFOLDS

Scaffold structures are available through partnership engagements — labs@smartledger.solutions

# Scaffold Count Avg Binding
1 🔒 partnership-gated 36,463 0.5746
2 🔒 partnership-gated 31,194 0.4652
3 🔒 partnership-gated 30,840 0.3862
4 🔒 partnership-gated 26,143 0.5058
5 🔒 partnership-gated 24,144 0.4653
6 🔒 partnership-gated 14,076 0.4597
7 🔒 partnership-gated 11,657 0.6016
8 🔒 partnership-gated 11,140 0.2761
9 🔒 partnership-gated 10,300 0.4491
10 🔒 partnership-gated 9,794 0.2891
Partnership Access
Compound dossiers, ADMet profiles, scaffold data, and bulk exports are available through partnership engagements with our research team.